When Joe Tippens, a cancer survivor from Oklahoma, told the story of how he beat a stage four pancreatic cancer with a dog dewormer, doctors and other health-care professionals were skeptical. But after three months of following his “Joe Tippens Cancer Protocol” — which includes taking fenbendazole, CBD oil, and curcumin seven days a week along with vitamin E supplements — his PET scan came back clear, and he has been cancer-free ever since.
While preclinical studies are exploring anthelminthic benzimidazole carbamate (BZ) drugs like fenbendazole, albendazole, and mebendazole as anticancer treatments, these medicines are not yet approved for use in humans, so their efficacy and side effects have not been fully tested. The BZ group of drugs targets parasites by blocking the formation of a protein called tubulin, which acts as both a micro-skeleton and a highway for transport within the cells. By collapsing tubulin, the drug cuts off the parasites’ supply of food and starves them to death.
In addition to targeting the structure of cancer cells, the BZ group of drugs may also reprogramme the tumour microenvironment, causing the cell to produce less vascular endothelial growth factor and PD-L1 (programmed death-ligand 1), which suppress tumours’ ability to grow and metastasize. By reprogramming the tumour microenvironment, BZs could significantly increase tumour sensitivity to current standard therapies.
Although there’s no clinical proof that fenbendazole works as an anticancer drug in humans, it has been shown to effectively inhibit cancerous liver tissue growth when combined with the standard care treatment sorafenib in experimental mice. Additionally, it’s known to interfere with the formation of microtubules, the cellular structures that give shape to all living things and are required for proper cell division. dewormer for cancer