CBD oil is the other name for cannabidiol. It is a phytocannabinoid discovered in 1940. The CBD oil is extracted from the cannabis plants and accounts for up to 40% of the plant’s extract.
This compound is believed to have a range of health benefits and is useful in various medical treatments. Researchers have, in recent times, conducted studies to evaluate the usefulness of this compound in the treatment of cognitive problems, body movement disorders, anxiety and pain.
How to intake CBD oil?
CBD oil can be taken by various means into the human body. Some common methods include-
- Inhalation of cannabis smoke
- As a vapour
- As an aerosol spray into the cheek
- Oral ingestion
The use and extraction of CBD was studied for the very first time from the Minnesota wild hemp and the resin of Egyptian Cannabis indica plant.
CBD oil supply
The compound is available in the market or supplied in stores in various means. The substance may be supplied as CBD oil with the only active ingredient being cannabidiol. Such a compound is supplied without the inclusion of tetra hydro cannabinol or THC.
The product can be also supplied as full-plant CBD-dominant hemp extract oil, capsules, dried cannabis or a liquid solution as per prescription.
Medical uses of CBD oil
In the United States of America, cannabidiol is marketed under the name of Epidiolex. This drug is approved by the Food and Drug Administration in 2018 for the treatment of epilepsy. But the drug is not approved to be administered to patients less than 2 years of age.
Besides being used in the treatment of epilepsy, CBD oil is also used in the treatment of several neurological disorders. But their effects are yet to be confirmed.
Pharmacology of the compound
Scientifically speaking, the pharmacological effects of this compound include PPARᵧagonism and intracellular calcium release.
The oral bioavailability of CBD is approximately around 6% in humans while the bioavailability when inhaled is around 31%.
Cannabidiol is metabolized in the liver, like many other drugs, and also in the intestines.
Specific extract of the Cannabis plant, Nabiximols, is a patented medicine that contains CBD and THC in equal proportions. This drug is approved to be used in the treatment of central neuropathic pain in multiple sclerosis and also in pains related o cancer.
Nabiximols are marketed under the trade name of Sativex.
CBD oil is insoluble in water but can be dissolved in some organic solvents such as pentane. At room temperature, CBD oil occurs as a colourless crystalline solid. CBD Oil UK